Vitacore Dimolish™ is a powerful anti-aromatase formula designed to decrease estrogen and create a superior muscle-building environment. The ingredients we’ve selected for Dimolish™ help inhibit the enzymes (aromatase) that converts testosterone into estrogen. Lower estrogen levels in the body help:
Support muscle growth and strength
Promote optimal performance
Reduce recovery time between sessions
Aid in fat mass loss
Decrease water weight
Using clinically tested and dosed ingredients, Dimolish™ will help keep estrogen levels in check and assist in creating in optimal anabolic environment.
- 200mg Diindolemethane (DIM)– An aromatase inhibitor, prevents conversion of testosterone into estrogen.
- 100mg Indole-3-Carbinol – Modulates estrogen metabolism and may optimize the ratio of testosterone to estrogen in the body.
- 6mg Black Pepper Extract – Increases absorption of active ingredients by 30 to 2000 percent.
- Vitamin E – May alter the body’s cellular response to estrogen by inhibiting estrogen receptor-positive cell growth.
Ingredient Profile :
Vitamin E is a fat soluble vitamin made up of a group of tocopherols and tocotrienols that acts as an antioxidant.
• Vitamin E may also alter the body’s cellular response to estrogen by inhibiting estrogen receptor-positive cell growth
DIM is a molecule that consists of two indole groups attached to a methane group. It is commonly found in broccoli and hold promise as an aromatase inhibitor.
• DIM has potent effects on estrogen metabolism and is able to keep the body relatively balanced by preventing either drastic increases or decreases in estrogen.
• DIM can both inhibit the aromatase enzyme (and prevent conversion of testosterone into estrogen) and it can act on more potent forms of estrogen and convert them into less potent forms; this conversion reduces the overall effects of estrogen in the body.
Indole-3-Carbinol is a compound found in broccoli and other cruciferous vegetables that modulates estrogen metabolism and may optimize the ratio of testosterone to estrogen in the body.
• By reducing the amount of estrogen in the body, Indole-3-Carbinol promotes an optimal muscle building and fat loss environment.
• A study done by Chang et al. (2011) using Indole-3-Carbinol (a precursor to DIM) noted that 5mg injections into the gut daily was able to attenuate the expected gain in body fat associated with a high fat/calorie diet.
Black Pepper Extract:
Black pepper extract significantly enhances the bioavailability of various supplement nutrients through increased absorption.
• Numerous clinical studies suggest that when black pepper extract is taken with other supplements, it increases the absorption of those supplements by 30 to 2,000 percent.
Q: How should I take VitaCore Dimolish™?
A: As a dietary supplement take 1 serving (1 capsule) 1-2 times daily with a full glass of water.
Q: What is an aromatase inhibitor and why is it important?
A: Aromatase is the enzyme responsible for converting testosterone to estrogen. Inhibition of the aromatase enzyme helps reduce the amount of testosterone that gets converted to estrogen. Certain ingredients found in VitaCore Dimolish act as aromatase inhibitors.
Chamras, H., Barsky, S. H., Ardashian, A., Navasartian, D., Heber, D., & Glaspy, J. A. (2005). Novel interactions of vitamin E and estrogen in breast cancer. Nutrition and cancer, 52(1), 43-48.
1. Lo, R., & Matthews, J. (2010). A New Class of Estrogen Receptor Beta–Selective Activators. Molecular interventions, 10(3), 133.
2. Leong, H., Riby, J. E., Firestone, G. L., & Bjeldanes, L. F. (2004). Potent ligand-independent estrogen receptor activation by 3, 3′-diindolylmethane is mediated by cross talk between the protein kinase A and mitogen-activated protein kinase signaling pathways. Molecular Endocrinology, 18(2), 291-302.
3. Leong, H., Firestone, G. L., & Bjeldanes, L. F. (2001). Cytostatic effects of 3, 3′-diindolylmethane in human endometrial cancer cells result from an estrogen receptor-mediated increase in transforming growth factor-α expression. Carcinogenesis, 22(11), 1809-1817.
4. Sanderson, J. T., Slobbe, L., Lansbergen, G. W., Safe, S., & Van den Berg, M. (2001). 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin and diindolylmethanes differentially induce cytochrome P450 1A1, 1B1, and 19 in H295R human adrenocortical carcinoma cells. Toxicological sciences, 61(1), 40-48.
5. Safe, S., Wang, F., Porter, W., Duan, R., & McDougal, A. (1998). Ah receptor agonists as endocrine disruptors: antiestrogenic activity and mechanisms. Toxicology letters, 102, 343-347.
1. Chang, H. P., Wang, M. L., Chan, M. H., Chiu, Y. S., & Chen, Y. H. (2011). Antiobesity activities of indole-3-carbinol in high-fat-diet–induced obese mice. Nutrition, 27(4), 463-470.
Black Pepper Extract:
1. Johnson, J. J., Nihal, M., Siddiqui, I. A., Scarlett, C. O., Bailey, H. H., Mukhtar, H., & Ahmad, N. (2011). Enhancing the bioavailability of resveratrol by combining it with piperine. Molecular nutrition & food research, 55(8), 1169-1176.
2. Badmaev, V., & Majeed, M. (1996). Comparison of nutrient bioavailability when ingested alone and in combination with Bioperine. Research Report, Sabinsa Corporation.